Cartilage Transplantation

cartilage

Osteoarthritis is the most common joint condition, especially affecting the knee. As cartilage wears away over time, it leads to chronic pain and reduced mobility. Since cartilage has no pain receptors, damage becomes noticeable only when the underlying bone is affected.

A cartilage transplant (cartilage cell or chondrocyte transplant) is an advanced surgical procedure where damaged cartilage is repaired using healthy cartilage cells taken from the patient’s own body.

Before Cartilage Transplantation

After Cartilage Transplantation

Goals of Cartilage Cell Transplant (Knee)

  • Reduce knee pain

  • Restore weight-bearing and sports activity

  • Improve flexibility

  • Regenerate the cartilage layer

  • Prevent or delay joint replacement

  • Preserve natural knee function

Who Needs a Cartilage Transplant?

Young individuals: Sports injuries, accidents, osteochondritis dissecans (OCD)
Older adults: Age-related joint degeneration

Symptoms

Acute injury: Pain, swelling, movement restriction, joint locking
Chronic degeneration: Persistent pain, stiffness, difficulty with daily activities

Next Steps After a Cartilage Injury

Immediate evaluation by an orthopedic surgeon is recommended.

Required Investigations

  • X-ray: To check for fractures, arthritis, bone overgrowth, or bone defects

  • MRI: To assess cartilage defects and associated ligament or meniscus injuries

Why Cartilage Injuries Need Treatment

Cartilage injuries do not heal on their own due to poor blood supply. Untreated damage worsens over time and affects quality of life.

Treatment Options

Treatment depends on age, activity level, and size/depth of the defect.

  • Young + active patients: Cartilage cell therapy

  • Older + low activity: Knee replacement may be considered

Cartilage Cell Therapy (Two-Stage Procedure)

Stage 1: Arthroscopy + cartilage biopsy from a non-weight-bearing area; cells are sent to the lab for culture
Stage 2: After 4–6 weeks, arthroscopy + implantation of cultured cartilage cells using tissue adhesive

Return to Sports

Rehabilitation begins immediately. Low-impact sports may resume around 3 months, as advised by the doctor.

Recovery After Cartilage Transplant

  • Hospital stay: ~3 days

  • Crutches: ~8 weeks

  • Stationary cycling: 4–6 weeks

  • Swimming/Elliptical: 8–12 weeks

  • Light jogging: ~1 year

Total Recovery Time

  • Light activity: 6–8 weeks

  • Full recovery: 3–6 months